Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
gptkb:enzyme |
| gptkbp:ATCCode |
gptkb:J01DH51
|
| gptkbp:CASNumber |
82009-34-5
|
| gptkbp:combines |
gptkb:imipenem
|
| gptkbp:developed_to |
protect imipenem from renal metabolism
|
| gptkbp:discoveredBy |
1980s
|
| gptkbp:eliminationHalfLife |
1 hour
|
| gptkbp:excretion |
renal
|
| gptkbp:hasMolecularFormula |
C16H26N2O5S
|
| https://www.w3.org/2000/01/rdf-schema#label |
cilastatin
|
| gptkbp:inhibitedBy |
gptkb:dehydropeptidase_I
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:MeSH_ID |
D015242
|
| gptkbp:prevents_degradation_of |
gptkb:imipenem
|
| gptkbp:PubChem_CID |
CHEMBL1201192
5284375 DB01597 |
| gptkbp:routeOfAdministration |
intravenous
|
| gptkbp:sideEffect |
nausea
vomiting phlebitis rash |
| gptkbp:UNII |
U5SYW473RQ
|
| gptkbp:usedFor |
renal dehydropeptidase inhibitor
bacterial infections (in combination with imipenem) |
| gptkbp:bfsParent |
gptkb:Primaxin
gptkb:Recarbrio |
| gptkbp:bfsLayer |
5
|