|
gptkbp:instanceOf
|
gptkb:protein
gptkb:enzyme
|
|
gptkbp:administeredBy
|
intravenous infusion
|
|
gptkbp:approvedBy
|
gptkb:FDA
1994
|
|
gptkbp:ATCCode
|
A16AB02
|
|
gptkbp:brand
|
gptkb:Cerezyme
|
|
gptkbp:CASNumber
|
143204-99-1
|
|
gptkbp:developedBy
|
gptkb:Genzyme
|
|
gptkbp:drugClass
|
enzyme replacement therapy
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
imiglucerase
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
replaces deficient glucocerebrosidase
|
|
gptkbp:molecularWeight
|
60 kDa
|
|
gptkbp:notEffectiveAgainst
|
gptkb:Type_2_Gaucher_disease
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:producedBy
|
gptkb:Chinese_hamster_ovary_cells
|
|
gptkbp:product
|
recombinant DNA technology
|
|
gptkbp:relatedTo
|
velaglucerase alfa
taliglucerase alfa
|
|
gptkbp:routeOfAdministration
|
intravenous
|
|
gptkbp:sideEffect
|
nausea
fatigue
headache
pruritus
rash
infusion reaction
|
|
gptkbp:target
|
gptkb:glucocerebroside
|
|
gptkbp:treatment
|
gptkb:Type_1_Gaucher_disease
gptkb:Type_3_Gaucher_disease
|
|
gptkbp:UNII
|
QPW8B8644R
|
|
gptkbp:usedFor
|
gptkb:Gaucher's_disease
|
|
gptkbp:bfsParent
|
gptkb:Cerezyme
|
|
gptkbp:bfsLayer
|
7
|