Statements (53)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Cell
|
| gptkbp:alsoKnownAs |
CHO cells
|
| gptkbp:canBe |
cloned
genetically engineered cryopreserved adapted to serum-free media adapted to suspension culture |
| gptkbp:commonIn |
protein engineering
vaccine production biopharmaceutical manufacturing glycosylation studies gene amplification |
| gptkbp:cultivatedIn |
adherent culture
suspension culture |
| gptkbp:derivedFrom |
gptkb:Chinese_hamster_(Cricetulus_griseus)
|
| gptkbp:firstIsolatedFrom |
1957
|
| gptkbp:genomeSense |
aneuploid
|
| gptkbp:hostedBy |
recombinant DNA
mammalian expression vectors |
| https://www.w3.org/2000/01/rdf-schema#label |
Chinese hamster ovary cells
|
| gptkbp:originatedIn |
Dr. Theodore T. Puck's laboratory
|
| gptkbp:subspecies |
gptkb:CHO-DG44
gptkb:CHO-K1 gptkb:CHO-Pro5 gptkb:CHO-S |
| gptkbp:transfectable |
yes
|
| gptkbp:usedBy |
academic researchers
biopharmaceutical companies contract manufacturing organizations |
| gptkbp:usedFor |
metabolic engineering
glycoengineering cell signaling research gene editing research cell engineering toxicology testing drug screening cell line development bioprocess optimization therapeutic protein production protein glycosylation analysis CRISPR studies biosimilar production large-scale protein production |
| gptkbp:usedIn |
gptkb:biotechnology
toxicology studies gene expression studies pharmaceutical production recombinant protein production monoclonal antibody production |
| gptkbp:bfsParent |
gptkb:recombinant_human_growth_hormone
gptkb:epoetin_alfa gptkb:interferon_beta-1a |
| gptkbp:bfsLayer |
7
|