hexokinase IV (glucokinase)

URI: https://gptkb.org/entity/hexokinase_IV_(glucokinase)
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:activatedBy glucose
gptkbp:alsoKnownAs gptkb:glucokinase
gptkbp:biologicalProcess ATP binding
glucose binding
gptkbp:CASNumber 9001-44-7
gptkbp:catalyzes phosphorylation of glucose to glucose-6-phosphate
gptkbp:cofactor Mg2+
gptkbp:discoveredBy gptkb:Bernardo_Houssay
gptkbp:doesNotInhibitBy gptkb:glucose-6-phosphate
gptkbp:EC_number 2.7.1.2
gptkbp:expressedIn gptkb:human
gptkb:mouse
right
gptkbp:foundIn liver
pancreatic beta cells
gptkbp:gene gptkb:GCK
https://www.w3.org/2000/01/rdf-schema#label hexokinase IV (glucokinase)
gptkbp:inhibitedBy fructose-6-phosphate
gptkbp:KmForGlucose high
gptkbp:locatedOnChromosome 7p15.3
gptkbp:mutationAssociatedWith gptkb:hyperinsulinemic_hypoglycemia
gptkb:maturity_onset_diabetes_of_the_young_(MODY2)
gptkbp:pathway glycolysis
glucose homeostasis
gptkbp:regulates gptkb:glucokinase_regulatory_protein_(GKRP)
blood glucose levels
gptkbp:structure monomer
gptkbp:subcellularLocation gptkb:nucleus
gptkb:cytoplasm
gptkbp:UniProtID gptkb:P35557
gptkbp:bfsParent gptkb:hexokinase
gptkbp:bfsLayer 6