|
gptkbp:instanceOf
|
gptkb:virus
|
|
gptkbp:alsoKnownAs
|
gptkb:varicella-zoster_virus
gptkb:VZV
|
|
gptkbp:associatedWith
|
gptkb:Ramsay_Hunt_syndrome
postherpetic neuralgia
herpes zoster ophthalmicus
|
|
gptkbp:category
|
DNA virus
enveloped virus
neurotropic virus
|
|
gptkbp:cause
|
gptkb:chickenpox
shingles
|
|
gptkbp:discoveredBy
|
James W. Downie
|
|
gptkbp:enveloped
|
true
|
|
gptkbp:family
|
gptkb:Herpesviridae
|
|
gptkbp:firstDescribed
|
1952
|
|
gptkbp:genomeSize
|
about 125 kb
|
|
gptkbp:genomeType
|
double-stranded DNA
|
|
gptkbp:genus
|
gptkb:Varicellovirus
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
herpes zoster virus
|
|
gptkbp:infects
|
humans
|
|
gptkbp:latencySite
|
sensory nerve ganglia
|
|
gptkbp:notableFor
|
gptkb:IE62_protein
glycoprotein B
glycoprotein E
|
|
gptkbp:numberOfGenes
|
about 70-80
|
|
gptkbp:order
|
gptkb:Herpesvirales
|
|
gptkbp:primaryInfection
|
gptkb:chickenpox
|
|
gptkbp:range
|
narrow
|
|
gptkbp:relatedTo
|
herpes simplex virus 1
herpes simplex virus 2
|
|
gptkbp:replicationSite
|
gptkb:nucleus
|
|
gptkbp:revival
|
shingles
|
|
gptkbp:riskFactor
|
elderly
immunocompromised individuals
|
|
gptkbp:size
|
approximately 150-200 nm
|
|
gptkbp:structure
|
icosahedral capsid
|
|
gptkbp:subfamily
|
gptkb:Alphaherpesvirinae
|
|
gptkbp:transmission
|
respiratory droplets
direct contact with lesions
|
|
gptkbp:treatment
|
gptkb:famciclovir
gptkb:valacyclovir
gptkb:acyclovir
|
|
gptkbp:vaccineAvailable
|
true
|
|
gptkbp:vaccineType
|
live attenuated
recombinant subunit
|
|
gptkbp:bfsParent
|
gptkb:dorsal_root_ganglia
|
|
gptkbp:bfsLayer
|
7
|