|
gptkbp:instanceOf
|
gptkb:virus
|
|
gptkbp:abbreviation
|
gptkb:HCV
|
|
gptkbp:associatedWith
|
gptkb:liver_disease
cirrhosis
hepatocellular carcinoma
|
|
gptkbp:cause
|
gptkb:hepatitis_C
|
|
gptkbp:discoveredBy
|
gptkb:Charles_M._Rice
gptkb:Harvey_J._Alter
gptkb:Michael_Houghton
|
|
gptkbp:discoveredIn
|
1989
|
|
gptkbp:enveloped
|
true
|
|
gptkbp:family
|
gptkb:Flaviviridae
|
|
gptkbp:firstIsolatedFrom
|
blood
|
|
gptkbp:gene
|
2
1
3
4
5
6
7
|
|
gptkbp:genomeType
|
single-stranded RNA
|
|
gptkbp:genus
|
gptkb:Hepacivirus
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
hepatitis C virus
|
|
gptkbp:ICTVdB
|
20190234
|
|
gptkbp:infects
|
humans
|
|
gptkbp:notableFor
|
gptkb:Nobel_Prize_in_Physiology_or_Medicine_2020_(for_discovery)
leading cause of liver transplantation
major cause of chronic hepatitis
|
|
gptkbp:order
|
gptkb:Amarillovirales
|
|
gptkbp:range
|
humans
chimpanzees
|
|
gptkbp:relatedTo
|
gptkb:dengue_virus
gptkb:hepatitis_B_virus
gptkb:yellow_fever_virus
|
|
gptkbp:replicationSite
|
gptkb:cytoplasm
|
|
gptkbp:shape
|
icosahedral
|
|
gptkbp:size
|
about 50 nm
|
|
gptkbp:taxonRank
|
gptkb:species
|
|
gptkbp:transmissionRoute
|
blood-to-blood contact
shared needles
sexual contact (rare)
unscreened blood transfusions
|
|
gptkbp:treatment
|
direct-acting antivirals
interferon (historical)
ribavirin (historical)
|
|
gptkbp:vaccineAvailable
|
false
|
|
gptkbp:bfsParent
|
gptkb:RT-PCR
gptkb:hepatitis_C
gptkb:bloodborne_pathogens_standard
|
|
gptkbp:bfsLayer
|
5
|