Statements (49)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:virus
|
| gptkbp:associatedWith |
liver cirrhosis
hepatocellular carcinoma chronic hepatitis |
| gptkbp:cause |
gptkb:Hepatitis_C
|
| gptkbp:diagnosedBy |
antibody test
liver function tests RNA PCR test |
| gptkbp:discoveredBy |
gptkb:Charles_M._Rice
gptkb:Harvey_J._Alter gptkb:Michael_Houghton |
| gptkbp:discoveredIn |
1989
|
| gptkbp:family |
gptkb:Flaviviridae
|
| gptkbp:fullName |
gptkb:Hepatitis_C_virus
|
| gptkbp:genomeType |
single-stranded RNA
|
| gptkbp:genus |
gptkb:Hepacivirus
|
| https://www.w3.org/2000/01/rdf-schema#label |
HCV
|
| gptkbp:infects |
humans
|
| gptkbp:NobelPrizeYear |
2020 (for discovery of HCV)
|
| gptkbp:numberOfGenes |
7
|
| gptkbp:prevalence |
~58 million people worldwide (2023)
|
| gptkbp:prevention |
harm reduction for drug users
safe injection practices screening blood products |
| gptkbp:riskFactor |
HIV infection
hemodialysis healthcare work exposure injection drug use receiving unscreened blood |
| gptkbp:structure |
enveloped virus
|
| gptkbp:symptom |
nausea
abdominal pain fatigue jaundice dark urine |
| gptkbp:transmission |
blood-to-blood contact
sharing needles sexual contact (rare) blood transfusion (before screening) unsterile medical equipment vertical transmission (mother to child) |
| gptkbp:treatment |
direct-acting antivirals
|
| gptkbp:treatmentSuccessRate |
>95% with modern antivirals
|
| gptkbp:vaccineAvailable |
no
|
| gptkbp:WHOClassification |
Group IV (positive-sense single-stranded RNA viruses)
|
| gptkbp:bfsParent |
gptkb:hepatitis_C_virus
gptkb:Hepatitis_C_virus gptkb:Sovaldi |
| gptkbp:bfsLayer |
6
|