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gptkbp:instanceOf
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genetic disorder
bleeding disorder
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gptkbp:affects
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blood clotting
mostly males
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gptkbp:alsoKnownAs
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gptkb:Christmas_disease
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gptkbp:causedBy
|
mutation in F9 gene
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gptkbp:complication
|
gptkb:anemia
inhibitor development
hemarthrosis
intracranial hemorrhage
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gptkbp:deficiencyCauses
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gptkb:factor_IX
|
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gptkbp:diagnosedBy
|
genetic testing
factor IX assay
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gptkbp:differentialDiagnosis
|
gptkb:von_Willebrand_disease
gptkb:hemophilia_A
|
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gptkbp:firstDescribed
|
1952
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|
https://www.w3.org/2000/01/rdf-schema#label
|
hemophilia B
|
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gptkbp:ICD-10_code
|
D67
|
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gptkbp:inheritance
|
X-linked recessive
|
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gptkbp:inheritsFrom
|
X-linked recessive
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gptkbp:MeSH_ID
|
D006467
|
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gptkbp:namedAfter
|
gptkb:Stephen_Christmas
|
|
gptkbp:notableCase
|
gptkb:Queen_Victoria's_descendants
|
|
gptkbp:OMIM
|
306900
|
|
gptkbp:prevalence
|
1 in 25,000 male births
|
|
gptkbp:riskFactor
|
family history
|
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gptkbp:symptom
|
prolonged bleeding
joint bleeding
spontaneous bleeding
|
|
gptkbp:treatment
|
factor IX replacement therapy
recombinant factor IX
|
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gptkbp:bfsParent
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gptkb:hemophilia_A
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gptkbp:bfsLayer
|
5
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