Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:hemoglobin |
| gptkbp:alternativeName |
gptkb:fetal_hemoglobin
|
| gptkbp:composedOf |
alpha globin chain
gamma globin chain |
| gptkbp:discoveredBy |
James Herrick
|
| gptkbp:foundIn |
fetus
newborn |
| gptkbp:function |
oxygen transport
|
| gptkbp:hasAlphaChainCount |
2
|
| gptkbp:hasGammaChainCount |
2
|
| gptkbp:higherAffinityForOxygenThan |
gptkb:hemoglobin_A
|
| gptkbp:locatedOnChromosome |
chromosome 11 (gamma globin gene)
chromosome 16 (alpha globin gene) |
| gptkbp:percentageInAdults |
<1%
|
| gptkbp:percentageInNewborns |
60-80%
|
| gptkbp:replacedBy |
gptkb:hemoglobin_A
|
| gptkbp:significance |
elevated in some hemoglobinopathies
used in diagnosis of sickle cell disease used in diagnosis of thalassemia |
| gptkbp:structure |
tetramer
|
| gptkbp:symbol |
gptkb:HbF
|
| gptkbp:bfsParent |
gptkb:HBA1_gene
gptkb:fetal_hemoglobin gptkb:hemoglobin_A |
| gptkbp:bfsLayer |
9
|
| https://www.w3.org/2000/01/rdf-schema#label |
hemoglobin F
|