Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
hemoglobin
|
gptkbp:abbreviation |
gptkb:HbF
|
gptkbp:alsoKnownAs |
gptkb:hemoglobin_F
|
gptkbp:composedOf |
two alpha chains
two gamma chains |
gptkbp:foundIn |
fetus
newborn |
gptkbp:function |
oxygen transport
|
gptkbp:gene |
gptkb:HBG1
gptkb:HBG2 |
gptkbp:higherAffinityFor |
oxygen
|
https://www.w3.org/2000/01/rdf-schema#label |
fetal hemoglobin
|
gptkbp:locatedOnChromosome |
chromosome 11
|
gptkbp:percentageInAdults |
<1%
|
gptkbp:percentageInNewborns |
60-80%
|
gptkbp:replacedBy |
gptkb:adult_hemoglobin
|
gptkbp:significance |
elevated in some hemoglobinopathies
used in diagnosis of sickle cell disease used in diagnosis of thalassemia |
gptkbp:structure |
tetramer
|
gptkbp:synthesisType |
erythroid precursors
|
gptkbp:bfsParent |
gptkb:hemoglobin
|
gptkbp:bfsLayer |
5
|