fetal hemoglobin

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf hemoglobin
gptkbp:abbreviation gptkb:HbF
gptkbp:alsoKnownAs gptkb:hemoglobin_F
gptkbp:composedOf two alpha chains
two gamma chains
gptkbp:foundIn fetus
newborn
gptkbp:function oxygen transport
gptkbp:gene gptkb:HBG1
gptkb:HBG2
gptkbp:higherAffinityFor oxygen
https://www.w3.org/2000/01/rdf-schema#label fetal hemoglobin
gptkbp:locatedOnChromosome chromosome 11
gptkbp:percentageInAdults <1%
gptkbp:percentageInNewborns 60-80%
gptkbp:replacedBy gptkb:adult_hemoglobin
gptkbp:significance elevated in some hemoglobinopathies
used in diagnosis of sickle cell disease
used in diagnosis of thalassemia
gptkbp:structure tetramer
gptkbp:synthesisType erythroid precursors
gptkbp:bfsParent gptkb:hemoglobin
gptkbp:bfsLayer 5