growth hormone secretagogue receptor
GPTKB entity
Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:G_protein-coupled_receptor |
| gptkbp:alternativeName |
ghrelin receptor
GHS-R |
| gptkbp:associatedWith |
gptkb:Prader-Willi_syndrome
obesity growth hormone deficiency |
| gptkbp:encodedBy |
GHSR gene
|
| gptkbp:Entrez_Gene_ID |
2693
|
| gptkbp:expressedIn |
gptkb:pituitary_gland
hypothalamus peripheral tissues |
| gptkbp:foundIn |
humans
mammals |
| gptkbp:function |
binds ghrelin
mediates growth hormone release |
| gptkbp:HGNC_ID |
4265
|
| https://www.w3.org/2000/01/rdf-schema#label |
growth hormone secretagogue receptor
|
| gptkbp:ligand |
ghrelin
growth hormone secretagogues |
| gptkbp:locatedOnChromosome |
3q26.31
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:OMIM |
601898
|
| gptkbp:orthologIn |
gptkb:mouse
right |
| gptkbp:PDB |
6KO5
|
| gptkbp:RefSeq |
NM_198407
|
| gptkbp:type |
activates phospholipase C pathway
increases intracellular calcium |
| gptkbp:UniProtID |
Q92847
|
| gptkbp:bfsParent |
gptkb:Ghrelin
|
| gptkbp:bfsLayer |
6
|