Statements (47)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
|
| gptkbp:associatedWith |
sleep apnea
learning difficulties hypogonadism imprinting disorder skin picking behavior |
| gptkbp:causedBy |
deletion of paternal chromosome 15
|
| gptkbp:clinicalTrials |
ongoing studies
behavioral therapy trials dietary intervention studies genetic therapy trials hormonal therapy trials |
| gptkbp:demographics |
1 in 15,000 to 1 in 30,000 births
|
| gptkbp:diseaseResistance |
genetic testing
|
| gptkbp:first_appearance |
1956
|
| gptkbp:geneticDiversity |
15q11.2-q13
|
| https://www.w3.org/2000/01/rdf-schema#label |
Prader-Willi syndrome
|
| gptkbp:impact |
psychological support
dietary management hormone therapy |
| gptkbp:introduced |
A. Prader
|
| gptkbp:legalEvent |
reduced life expectancy
|
| gptkbp:nobleFamily |
not inherited
|
| gptkbp:relatedPatent |
gptkb:Turner_syndrome
gptkb:Bardet-Biedl_syndrome gptkb:Angelman_syndrome gptkb:Klinefelter_syndrome gptkb:Smith-Magenis_syndrome |
| gptkbp:researchFocus |
behavioral interventions
genetic mechanisms hormonal treatments treatment options dietary strategies |
| gptkbp:riskManagement |
advanced paternal age
de novo mutations |
| gptkbp:supports |
gptkb:Prader-Willi_Syndrome_Association
educational support medical care social skills training nutritional guidance family counseling |
| gptkbp:symptoms |
obesity
intellectual disability behavioral problems short stature hypotonia hyperphagia |