glycine hydroxymethyltransferase
GPTKB entity
Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:serine_hydroxymethyltransferase
|
| gptkbp:catalyzes |
conversion of glycine to serine
|
| gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
| gptkbp:discoveredBy |
1950s
|
| gptkbp:EC_number |
2.1.2.1
|
| gptkbp:foundIn |
mitochondria
cytosol |
| gptkbp:gene |
gptkb:SHMT1
gptkb:SHMT2 |
| https://www.w3.org/2000/01/rdf-schema#label |
glycine hydroxymethyltransferase
|
| gptkbp:inhibitedBy |
aminomethylphosphonic acid
antifolates |
| gptkbp:involves |
one-carbon metabolism
folate cycle |
| gptkbp:PDB |
1BJ4
1DFO |
| gptkbp:presentIn |
gptkb:Bacteria
animals plants |
| gptkbp:product |
gptkb:H2O
serine tetrahydrofolate |
| gptkbp:requires |
nucleotide biosynthesis
methylation reactions |
| gptkbp:structure |
homotetramer
|
| gptkbp:substrate |
gptkb:5,10-methylenetetrahydrofolate
glycine |
| gptkbp:UniProtID |
P34896
P34897 |
| gptkbp:bfsParent |
gptkb:serine_hydroxymethyltransferase
|
| gptkbp:bfsLayer |
8
|