serine hydroxymethyltransferase
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:SHMT
gptkb:glycine_hydroxymethyltransferase gptkb:serine_methylase |
| gptkbp:catalyzes |
conversion of serine to glycine
|
| gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
| gptkbp:EC_number |
2.1.2.1
|
| gptkbp:foundIn |
mitochondria
cytosol |
| gptkbp:gene |
gptkb:SHMT1
gptkb:SHMT2 |
| https://www.w3.org/2000/01/rdf-schema#label |
serine hydroxymethyltransferase
|
| gptkbp:involves |
one-carbon metabolism
folate cycle |
| gptkbp:product |
gptkb:5,10-methylenetetrahydrofolate
gptkb:H2O glycine |
| gptkbp:requires |
amino acid metabolism
nucleotide biosynthesis |
| gptkbp:structure |
homodimer
homotetramer |
| gptkbp:substrate |
serine
tetrahydrofolate |
| gptkbp:UniProtID |
P34896 (human SHMT1)
P34897 (human SHMT2) |
| gptkbp:bfsParent |
gptkb:pyridoxal_phosphate
gptkb:glycine,_serine_and_threonine_metabolism |
| gptkbp:bfsLayer |
7
|