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gptkbp:instanceOf
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peptide
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gptkbp:abbreviation
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gptkb:GLP-1
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gptkbp:affects
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gastrointestinal tract
central nervous system
pancreatic beta cells
pancreatic alpha cells
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gptkbp:agonistDrugs
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gptkb:albiglutide
gptkb:exenatide
gptkb:liraglutide
gptkb:lixisenatide
gptkb:semaglutide
gptkb:dulaglutide
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gptkbp:category
|
gptkb:insulin
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gptkbp:degradedBy
|
dipeptidyl peptidase-4
|
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gptkbp:discoveredIn
|
1980s
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gptkbp:encodedBy
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gptkb:GCG_gene
|
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gptkbp:function
|
slows gastric emptying
reduces appetite
stimulates insulin secretion
inhibits glucagon secretion
|
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gptkbp:halfLife
|
1-2 minutes
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
glucagon-like peptide-1
|
|
gptkbp:length
|
30 or 31 amino acids
|
|
gptkbp:predecessor
|
proglucagon
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gptkbp:producedBy
|
L cells of the intestine
|
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gptkbp:promotion
|
nutrient ingestion
|
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gptkbp:recipient
|
gptkb:GLP-1_receptor
|
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gptkbp:usedIn
|
treatment of obesity
treatment of type 2 diabetes
|
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gptkbp:bfsParent
|
gptkb:Glucose-dependent_insulinotropic_polypeptide
gptkb:GLP-1_receptor
gptkb:intestinal_L-cells
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gptkbp:bfsLayer
|
8
|