|
gptkbp:instanceOf
|
gptkb:antibiotic
|
|
gptkbp:ATCCode
|
J01XX01
|
|
gptkbp:brand
|
Fosfocina
Monurol
|
|
gptkbp:CASNumber
|
23155-02-4
|
|
gptkbp:chemicalFormula
|
C3H7O4P
|
|
gptkbp:discoveredBy
|
Shimizu et al.
|
|
gptkbp:discoveredIn
|
1969
|
|
gptkbp:effect
|
gptkb:Staphylococcus_saprophyticus
gptkb:Bacteria
gptkb:Enterococcus_faecalis
|
|
gptkbp:eliminationHalfLife
|
4 hours
|
|
gptkbp:excretion
|
renal
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
fosfomycin
|
|
gptkbp:IUPACName
|
(1R,2S)-epoxypropylphosphonic acid
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits bacterial cell wall synthesis
|
|
gptkbp:metabolism
|
not metabolized
|
|
gptkbp:molecularWeight
|
138.06 g/mol
|
|
gptkbp:origin
|
Streptomyces fradiae
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular
intravenous
|
|
gptkbp:sideEffect
|
nausea
diarrhea
headache
rash
|
|
gptkbp:spectrumOfActivity
|
broad-spectrum
|
|
gptkbp:usedFor
|
urinary tract infection
bladder infection
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
true
|
|
gptkbp:bfsParent
|
gptkb:carbapenem-resistant_Enterobacteriaceae
gptkb:Streptomyces
|
|
gptkbp:bfsLayer
|
7
|