formyl peptide receptor 1 protein

URI: https://gptkb.org/entity/formyl_peptide_receptor_1_protein
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:FPR1
gptkb:FMLP_receptor
formyl peptide receptor 1
gptkbp:associatedWith inflammation
bacterial infection response
gptkbp:biologicalProcess immune response
inflammatory response
G protein-coupled receptor activity
gptkbp:cellularComponent gptkb:plasma_membrane
gptkbp:encodedBy FPR1 gene
gptkbp:Entrez_Gene_ID 2357
gptkbp:expressedIn macrophages
monocytes
neutrophils
gptkbp:family gptkb:G_protein-coupled_receptor
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function binds N-formyl peptides
mediates chemotaxis of neutrophils
gptkbp:HGNC_ID 3829
https://www.w3.org/2000/01/rdf-schema#label formyl peptide receptor 1 protein
gptkbp:length 350 amino acids
gptkbp:ligand N-formylmethionyl-leucyl-phenylalanine (fMLF)
gptkbp:locatedOnChromosome gptkb:19q13.3
gptkbp:OMIM 136537
gptkbp:orthologIn mouse Fpr1
gptkbp:PDB 6OMM
gptkbp:structure seven transmembrane domains
gptkbp:subfamily formyl peptide receptor subfamily
gptkbp:UniProtID gptkb:P21462
gptkbp:bfsParent gptkb:FPR1
gptkbp:bfsLayer 8