Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:FAS
gptkb:fatty_acid_synthase |
| gptkbp:biologicalProcess |
oxidoreductase activity
acyltransferase activity |
| gptkbp:catalyzes |
fatty acid synthesis
|
| gptkbp:cofactor |
NADPH
|
| gptkbp:EC_number |
2.3.1.85
|
| gptkbp:foundIn |
animals
fungi plants |
| gptkbp:gene |
gptkb:FASN
|
| gptkbp:inhibitedBy |
gptkb:C75
gptkb:cerulenin gptkb:orlistat |
| gptkbp:involvedIn |
lipid metabolism
|
| gptkbp:locatedIn |
gptkb:cytoplasm
|
| gptkbp:overexpressedIn |
cancer cells
|
| gptkbp:product |
gptkb:palmitate
CO2 NADP+ |
| gptkbp:structure |
multienzyme complex
|
| gptkbp:substrate |
gptkb:malonyl-CoA
acetyl-CoA |
| gptkbp:subunit |
alpha subunit
beta subunit |
| gptkbp:bfsParent |
gptkb:FASN
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
fatty acid synthase enzyme
|