fam-trastuzumab deruxtecan-nxki

URI: https://gptkb.org/entity/fam-trastuzumab_deruxtecan-nxki
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkbp:activeIngredient gptkb:trastuzumab_deruxtecan
gptkbp:approvalYear 2019
gptkbp:approvedBy gptkb:FDA
gptkb:EMA
gptkbp:ATCCode gptkb:L01FG02
gptkbp:brand gptkb:Enhertu
gptkbp:CASNumber gptkb:2228327-56-2
gptkbp:coDeveloper gptkb:AstraZeneca
gptkbp:developer gptkb:Daiichi_Sankyo
gptkbp:drugClass antineoplastic agent
gptkbp:form lyophilized powder for solution for infusion
https://www.w3.org/2000/01/rdf-schema#label fam-trastuzumab deruxtecan-nxki
gptkbp:indication gptkb:HER2-positive_breast_cancer
gptkb:HER2-mutant_non-small_cell_lung_cancer
HER2-positive gastric cancer
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction gptkb:monoclonal_antibody
gptkbp:pregnancyCategory D (US)
gptkbp:routeOfAdministration intravenous
gptkbp:sideEffect nausea
vomiting
fatigue
neutropenia
interstitial lung disease
gptkbp:target HER2
gptkbp:UNII 6Y7T7T8A5B
gptkbp:usedFor gptkb:non-small_cell_lung_cancer
gptkb:cancer
gastric cancer
gptkbp:bfsParent gptkb:HER2/neu_receptor
gptkbp:bfsLayer 7