|
gptkbp:instanceOf
|
gptkb:protein
amino acid transporter
|
|
gptkbp:alias
|
gptkb:DAT
gptkb:DAT1
gptkb:SLC6A3
|
|
gptkbp:associatedWith
|
gptkb:Parkinson's_disease
gptkb:attention_deficit_hyperactivity_disorder
bipolar disorder
schizophrenia
substance abuse
|
|
gptkbp:biologicalProcess
|
neurotransmitter transport
dopamine transmembrane transporter activity
dopamine uptake
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000142319
gptkb:SLC6A3
|
|
gptkbp:expressedIn
|
gptkb:striatum
gptkb:ventral_tegmental_area
brain
substantia nigra
|
|
gptkbp:foundIn
|
presynaptic neuron
|
|
gptkbp:function
|
reuptake of dopamine from synaptic cleft
|
|
gptkbp:gene
|
gptkb:SLC6A3
|
|
gptkbp:HGNC_ID
|
11049
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
dopamine transporter
|
|
gptkbp:inhibitedBy
|
gptkb:bupropion
gptkb:benztropine
gptkb:modafinil
gptkb:nomifensine
gptkb:methylphenidate
cocaine
amphetamine
mazindol
|
|
gptkbp:locatedIn
|
gptkb:plasma_membrane
|
|
gptkbp:locatedOnChromosome
|
gptkb:5p15.33
|
|
gptkbp:OMIM
|
126455
|
|
gptkbp:PDB
|
gptkb:4XPA
|
|
gptkbp:proteinFamily
|
gptkb:solute_carrier_family_6
|
|
gptkbp:targetOfDrug
|
gptkb:bupropion
gptkb:benztropine
gptkb:modafinil
gptkb:nomifensine
gptkb:methylphenidate
cocaine
amphetamine
mazindol
|
|
gptkbp:transport_mechanism
|
sodium-dependent
chloride-dependent
|
|
gptkbp:UniProtID
|
gptkb:Q01959
|
|
gptkbp:bfsParent
|
gptkb:Ecstasy
|
|
gptkbp:bfsLayer
|
6
|