|
gptkbp:instanceOf
|
gptkb:drug
anticonvulsant
mood stabilizer
|
|
gptkbp:activeIngredient
|
gptkb:valproic_acid
|
|
gptkbp:approvedBy
|
1983
|
|
gptkbp:ATCCode
|
N03AG01
|
|
gptkbp:brand
|
gptkb:Depakote
|
|
gptkbp:CASNumber
|
76584-70-8
|
|
gptkbp:chemicalFormula
|
C16H31NaO4
|
|
gptkbp:contraindication
|
gptkb:liver_disease
pregnancy
|
|
gptkbp:drugClass
|
fatty acid derivative
|
|
gptkbp:drugInteraction
|
gptkb:phenytoin
gptkb:warfarin
gptkb:aspirin
gptkb:carbamazepine
gptkb:lamotrigine
|
|
gptkbp:eliminationHalfLife
|
9-16 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:FDAApproved
|
yes
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
divalproex sodium
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:manufacturer
|
gptkb:AbbVie
|
|
gptkbp:mechanismOfAction
|
blocks voltage-gated sodium channels
increases GABA levels
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:monitors
|
liver function
platelet count
blood ammonia
|
|
gptkbp:overdoseSymptoms
|
coma
respiratory depression
metabolic acidosis
|
|
gptkbp:pregnancyCategory
|
D
|
|
gptkbp:prescribes
|
adults
children
|
|
gptkbp:riskFactor
|
pancreatitis
hepatotoxicity
teratogenicity
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
tremor
hair loss
weight gain
drowsiness
|
|
gptkbp:synonym
|
sodium valproate and valproic acid compound
|
|
gptkbp:tabletForm
|
extended-release
delayed-release
|
|
gptkbp:usedFor
|
bipolar disorder
epilepsy
migraine prevention
|
|
gptkbp:bfsParent
|
gptkb:Depakote
|
|
gptkbp:bfsLayer
|
7
|