dCas9

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName catalytically inactive Cas9
dead Cas9
gptkbp:binds gptkb:guide_RNA
target DNA
gptkbp:derivedFrom gptkb:Cas9
gptkbp:function DNA binding
transcriptional regulation
gptkbp:hasNo nuclease activity
https://www.w3.org/2000/01/rdf-schema#label dCas9
gptkbp:mutationAssociatedWith D10A
H840A
gptkbp:organismOfOrigin gptkb:Streptococcus_pyogenes
gptkbp:usedFor base editing
chromatin modification
gene activation
gene repression
genome imaging
gptkbp:usedIn gptkb:CRISPR_interference
gptkb:CRISPR_activation
epigenome editing
gptkbp:bfsParent gptkb:catalytically_dead_Cas9
gptkbp:bfsLayer 7