complex II of electron transport chain
GPTKB entity
Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
gptkb:succinate_dehydrogenase
|
| gptkbp:cofactor |
gptkb:FAD
gptkb:heme_b iron-sulfur clusters |
| gptkbp:component |
electron transport chain
|
| gptkbp:connectsTo |
gptkb:Krebs_cycle
|
| gptkbp:doesNotPumpProtons |
true
|
| gptkbp:EC_number |
1.3.5.1
|
| gptkbp:electronAcceptor |
ubiquinone
|
| gptkbp:electronDonor |
succinate
|
| gptkbp:function |
catalyzes oxidation of succinate to fumarate
transfers electrons from succinate to ubiquinone (coenzyme Q) |
| gptkbp:gene |
gptkb:SDHA
gptkb:SDHB gptkb:SDHC gptkb:SDHD |
| https://www.w3.org/2000/01/rdf-schema#label |
complex II of electron transport chain
|
| gptkbp:inhibitedBy |
malonate
thenoyltrifluoroacetone (TTFA) |
| gptkbp:locatedIn |
inner mitochondrial membrane
|
| gptkbp:mutationAssociatedWith |
gptkb:Leigh_syndrome
gptkb:pheochromocytoma paraganglioma |
| gptkbp:presentIn |
eukaryotes
some prokaryotes |
| gptkbp:subunit |
gptkb:SDHA
gptkb:SDHB gptkb:SDHC gptkb:SDHD |
| gptkbp:bfsParent |
gptkb:SIRT3
|
| gptkbp:bfsLayer |
8
|