Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:antibiotic
|
| gptkbp:alsoKnownAs |
gptkb:trimethoprim/sulfamethoxazole
|
| gptkbp:ATCCode |
gptkb:J01EE01
|
| gptkbp:contains |
trimethoprim
sulfamethoxazole |
| gptkbp:contraindication |
severe kidney disease
severe liver disease sulfa allergy |
| gptkbp:discoveredBy |
1968
|
| gptkbp:drugClass |
sulfonamide
antibacterial combination |
| gptkbp:eliminationHalfLife |
sulfamethoxazole: 10 hours
trimethoprim: 8-10 hours |
| gptkbp:excretion |
urine
|
| https://www.w3.org/2000/01/rdf-schema#label |
co-trimoxazole
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibits folic acid synthesis
|
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
D (US)
|
| gptkbp:routeOfAdministration |
oral
intravenous |
| gptkbp:sideEffect |
nausea
vomiting rash photosensitivity hyperkalemia |
| gptkbp:usedFor |
gptkb:MRSA_infections
gptkb:pneumocystis_pneumonia gptkb:toxoplasmosis urinary tract infections shigellosis |
| gptkbp:WHOModelListOfEssentialMedicines |
yes
|
| gptkbp:bfsParent |
gptkb:Sulfonamides
|
| gptkbp:bfsLayer |
6
|