Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:catalyzes |
conversion of PI to PI(3)P
conversion of PI(4)P to PI(3,4)P2 |
| gptkbp:discoveredIn |
1990s
|
| gptkbp:domain |
kinase domain
C2 domain PX domain |
| gptkbp:EC_number |
2.7.1.153
|
| gptkbp:encodedBy |
gptkb:PIK3C2A
gptkb:PIK3C2B gptkb:PIK3C2G |
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
phosphorylation of phosphoinositides
|
| gptkbp:hasIsoform |
gptkb:PI3K-C2α
gptkb:PI3K-C2β gptkb:PI3K-C2γ |
| https://www.w3.org/2000/01/rdf-schema#label |
class II PI3K
|
| gptkbp:involvedIn |
cell signaling
endocytosis membrane trafficking |
| gptkbp:molecularWeight |
~170-210 kDa
|
| gptkbp:regulates |
cell survival
vesicle trafficking cell growth |
| gptkbp:subclassOf |
gptkb:protein
|
| gptkbp:bfsParent |
gptkb:protein
|
| gptkbp:bfsLayer |
4
|