chromosome conformation capture (3C) technology
GPTKB entity
Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
molecular biology technique
|
| gptkbp:analyzes |
gptkb:quantitative_PCR
sequencing physical interactions between chromosomal regions |
| gptkbp:basedOn |
PCR amplification
ligation restriction enzyme digestion crosslinking DNA |
| gptkbp:developedBy |
2002
|
| gptkbp:enables |
identification of chromatin loops
study of enhancer-promoter interactions |
| gptkbp:field |
genomics
epigenetics |
| gptkbp:hasVariant |
gptkb:ChIA-PET
gptkb:5C gptkb:Hi-C gptkb:4C |
| https://www.w3.org/2000/01/rdf-schema#label |
chromosome conformation capture (3C) technology
|
| gptkbp:inventedBy |
gptkb:Job_Dekker
|
| gptkbp:requires |
gptkb:DNA_ligase
restriction enzymes formaldehyde crosslinking |
| gptkbp:studies |
chromatin architecture
spatial proximity of DNA elements |
| gptkbp:usedFor |
studying 3D organization of chromatin
|
| gptkbp:usedIn |
cancer research
developmental biology gene regulation research |
| gptkbp:bfsParent |
gptkb:Job_Dekker
|
| gptkbp:bfsLayer |
7
|