catabolite activator protein

URI: https://gptkb.org/entity/catabolite_activator_protein
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
transcription factor
gptkbp:abbreviation gptkb:CRP
gptkbp:alternativeName gptkb:CAP
gptkb:cAMP_receptor_protein
gptkbp:binds gptkb:cAMP
gptkb:gene
gptkbp:category DNA-binding protein
bacterial protein
regulatory protein
gptkbp:discoveredBy gptkb:Stanley_Cohen
gptkbp:discoveredIn 1970
gptkbp:foundIn gptkb:Bacteria
gptkbp:function regulates transcription of genes involved in carbon metabolism
gptkbp:gene crp
https://www.w3.org/2000/01/rdf-schema#label catabolite activator protein
gptkbp:location gptkb:cytoplasm
gptkbp:mechanismOfAction activates transcription by facilitating RNA polymerase binding
gptkbp:molecularWeight ~45 kDa
gptkbp:PDB gptkb:1G6N
gptkbp:regulates gptkb:lac_operon
gptkb:ara_operon
gptkb:gal_operon
gptkb:mal_operon
activated by cAMP binding
inactivated in absence of cAMP
other catabolic operons
gptkbp:structure homodimer
gptkbp:taxonRank gptkb:Bacteria
gptkbp:UniProtID gptkb:P0ACJ8
gptkbp:bfsParent gptkb:lac_operon
gptkbp:bfsLayer 6