bone morphogenetic protein-2 (BMP-2)
GPTKB entity
Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
growth factor |
| gptkbp:approvedBy |
gptkb:FDA
certain orthopedic procedures |
| gptkbp:binds |
gptkb:BMP_receptors
|
| gptkbp:discoveredBy |
John Wozney
|
| gptkbp:encodedBy |
BMP2 gene
|
| gptkbp:expressedIn |
collagen
bone tissue |
| gptkbp:function |
induces bone and cartilage development
regulates osteoblast differentiation |
| https://www.w3.org/2000/01/rdf-schema#label |
bone morphogenetic protein-2 (BMP-2)
|
| gptkbp:locatedOnChromosome |
20p12
|
| gptkbp:memberOf |
gptkb:transforming_growth_factor_beta_superfamily
bone morphogenetic protein family |
| gptkbp:molecularWeight |
26 kDa (monomer)
|
| gptkbp:structure |
dimeric protein
|
| gptkbp:UniProtID |
P12643
|
| gptkbp:usedIn |
bone grafts
spinal fusion surgeries |
| gptkbp:bfsParent |
gptkb:matrix_Gla_protein
|
| gptkbp:bfsLayer |
6
|