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gptkbp:instanceOf
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gptkb:disease
|
|
gptkbp:abbreviation
|
gptkb:atypical_hemolytic_uremic_syndrome
|
|
gptkbp:affects
|
blood
kidneys
|
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gptkbp:associatedWith
|
gptkb:CFI
gptkb:CD46
gptkb:CFH
gptkb:DGKE
gptkb:THBD
gptkb:CFB
C3
|
|
gptkbp:category
|
gptkb:thrombotic_microangiopathy
|
|
gptkbp:cause
|
genetic disorder
autoimmune response
complement system dysregulation
|
|
gptkbp:causedBy
|
Shiga toxin-producing E. coli
|
|
gptkbp:complication
|
hypertension
chronic kidney disease
end-stage renal disease
|
|
gptkbp:diagnosedBy
|
blood test
kidney biopsy
|
|
gptkbp:differentialDiagnosis
|
gptkb:typical_hemolytic_uremic_syndrome
thrombotic thrombocytopenic purpura
|
|
gptkbp:field
|
nephrology
hematology
|
|
gptkbp:firstDescribed
|
1955
|
|
gptkbp:fullName
|
gptkb:atypical_hemolytic_uremic_syndrome
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
aHUS
|
|
gptkbp:ICD-10_code
|
D59.3
|
|
gptkbp:inheritance
|
autosomal dominant
autosomal recessive
|
|
gptkbp:mortalityRate
|
high without treatment
|
|
gptkbp:OMIM
|
235400
|
|
gptkbp:onset
|
any age
|
|
gptkbp:prevalence
|
rare
|
|
gptkbp:riskFactor
|
certain medications
infection
pregnancy
genetic predisposition
|
|
gptkbp:symptom
|
gptkb:anemia
thrombocytopenia
acute kidney injury
|
|
gptkbp:treatment
|
gptkb:eculizumab
gptkb:ravulizumab
supportive care
plasma exchange
|
|
gptkbp:bfsParent
|
gptkb:atypical_hemolytic_uremic_syndrome
|
|
gptkbp:bfsLayer
|
8
|