|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:ARSA
cerebroside-sulfatase
|
|
gptkbp:associatedWith
|
gptkb:metachromatic_leukodystrophy
|
|
gptkbp:cofactor
|
calcium
|
|
gptkbp:deficiencyCauses
|
gptkb:metachromatic_leukodystrophy
|
|
gptkbp:EC_number
|
3.1.6.8
|
|
gptkbp:encodedBy
|
gptkb:ARSA_gene
|
|
gptkbp:Entrez_Gene_ID
|
GC22M044425
|
|
gptkbp:Enzyme_class
|
gptkb:hydrolase
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
other mammals
|
|
gptkbp:function
|
hydrolyzes cerebroside sulfate
removes sulfate groups from arylsulfates
|
|
gptkbp:HGNC_ID
|
711
|
|
gptkbp:locatedOnChromosome
|
gptkb:22q13.33
|
|
gptkbp:location
|
gptkb:lysosome
|
|
gptkbp:molecularWeight
|
~50 kDa
|
|
gptkbp:OMIM
|
607574
|
|
gptkbp:PDB
|
1AUK
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:RefSeq
|
NP_000478.3
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:substrate
|
cerebroside 3-sulfate
|
|
gptkbp:tissue_specificity
|
gptkb:leukocytes
gptkb:kidney
brain
liver
|
|
gptkbp:UniProtID
|
P15289
|
|
gptkbp:bfsParent
|
gptkb:metachromatic_leukodystrophy
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
arylsulfatase A
|