Statements (60)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:drug
|
| gptkbp:bfsLayer |
5
|
| gptkbp:bfsParent |
gptkb:Pentacarinat
|
| gptkbp:activities |
inhibits parasite growth
|
| gptkbp:appointed_by |
intravenous injection
|
| gptkbp:approves |
gptkb:2001
gptkb:World_Health_Organization |
| gptkbp:can_be_used_with |
gptkb:lumefantrine
gptkb:mefloquine amodiaquine |
| gptkbp:clinical_trial |
ongoing
|
| gptkbp:composed_of |
chemical modification
semi-synthetic process |
| gptkbp:developed_by |
gptkb:artemisinin
Chinese scientists |
| gptkbp:duration |
3 days
5 days |
| gptkbp:global_presence |
recommended for severe malaria
widely used in Africa widely used in Asia |
| gptkbp:historical_event |
gptkb:product
ancient herbal remedies |
| https://www.w3.org/2000/01/rdf-schema#label |
artesunate
|
| gptkbp:ingredients |
C18 H26 O5
|
| gptkbp:interacts_with |
gptkb:warfarin
antiretrovirals anticonvulsants |
| gptkbp:invention |
patented
generic available |
| gptkbp:is_available_on |
intramuscular injection
oral tablet rectal suppository |
| gptkbp:is_effective_against |
high efficacy against Plasmodium falciparum
rapid action reduces mortality in severe malaria |
| gptkbp:is_used_for |
treating malaria
|
| gptkbp:marketed_as |
gptkb:artesunate_injection
|
| gptkbp:produced_by |
gptkb:sweet_wormwood
|
| gptkbp:provides_information_on |
recommended for children
included in malaria treatment guidelines recommended for pregnant women |
| gptkbp:research_focus |
pharmacokinetics
efficacy studies combination therapies drug resistance safety profile |
| gptkbp:side_effect |
gptkb:fandom
headache nausea allergic reactions vomiting diarrhea hypersensitivity thrombocytopenia |
| gptkbp:storage |
room temperature
protected from light |
| gptkbp:suitable_for |
gptkb:WHO
severe renal impairment severe liver impairment |
| gptkbp:type_of |
88495-63-0
|