artesunate

GPTKB entity

Statements (61)
Predicate Object
gptkbp:instance_of gptkb:immunotherapy
gptkbp:administered_by intravenous injection
gptkbp:approves gptkb:2001
gptkb:World_Health_Organization
gptkbp:available_on intramuscular injection
oral tablet
rectal suppository
gptkbp:can_be_combined_with gptkb:lumefantrine
gptkb:mefloquine
amodiaquine
gptkbp:casnumber 88495-63-0
gptkbp:chemical_formula C18 H26 O5
gptkbp:clinical_trial ongoing
gptkbp:composed_by chemical modification
semi-synthetic process
gptkbp:developed_by gptkb:artemisinin
Chinese scientists
gptkbp:duration 3 days
5 days
gptkbp:global_presence recommended for severe malaria
widely used in Africa
widely used in Asia
gptkbp:historical_use gptkb:traditional_medicine
ancient herbal remedies
https://www.w3.org/2000/01/rdf-schema#label artesunate
gptkbp:interacts_with gptkb:warfarin
antiretrovirals
anticonvulsants
gptkbp:invention patented
generic available
gptkbp:is_effective_against high efficacy against Plasmodium falciparum
rapid action
reduces mortality in severe malaria
gptkbp:is_recommended_by gptkb:WHO
gptkbp:marketed_as gptkb:artesunate_injection
gptkbp:mechanism_of_action inhibits parasite growth
gptkbp:produced_by gptkb:sweet_wormwood
gptkbp:provides_guidance_on recommended for children
included in malaria treatment guidelines
recommended for pregnant women
gptkbp:research_focus pharmacokinetics
efficacy studies
combination therapies
drug resistance
safety profile
gptkbp:side_effect gptkb:anemia
headache
nausea
allergic reactions
vomiting
diarrhea
hypersensitivity
thrombocytopenia
gptkbp:storage room temperature
protected from light
gptkbp:suitable_for severe renal impairment
severe liver impairment
gptkbp:used_for treating malaria
gptkbp:bfsParent gptkb:Pentacarinat
gptkb:artemisinin-based_therapies
gptkbp:bfsLayer 7