|
gptkbp:instance_of
|
gptkb:chemical_compound
|
|
gptkbp:antimalarial_activity
|
high efficacy
|
|
gptkbp:antiparasitic_effect
|
effective against Plasmodium species
|
|
gptkbp:bioavailability
|
variable absorption
|
|
gptkbp:challenges
|
supply chain issues
|
|
gptkbp:chemical_formula
|
C15 H22 O5
|
|
gptkbp:class
|
sesquiterpene lactone
|
|
gptkbp:clinical_trial
|
ongoing studies
|
|
gptkbp:clinical_use
|
first-line treatment for uncomplicated malaria
|
|
gptkbp:community_health
|
important for public health initiatives
|
|
gptkbp:community_impact
|
significant in malaria control
|
|
gptkbp:composed_by
|
semi-synthetic methods
|
|
gptkbp:cultural_significance
|
part of traditional medicine practices
|
|
gptkbp:defense
|
recommended for malaria treatment
|
|
gptkbp:developed_by
|
gptkb:sweet_wormwood
|
|
gptkbp:discovered_by
|
gptkb:Tu_Youyou
|
|
gptkbp:discovery_award
|
gptkb:Nobel_Prize_in_Physiology_or_Medicine_2015
|
|
gptkbp:dissolved
|
soluble in organic solvents
|
|
gptkbp:excretion
|
renal excretion
|
|
gptkbp:financial_stability
|
sensitive to light and heat
|
|
gptkbp:formulation
|
oral and injectable forms
|
|
gptkbp:funding
|
supported by various organizations
|
|
gptkbp:future_prospects
|
new formulations and delivery methods
|
|
gptkbp:historical_significance
|
revolutionized malaria treatment
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
artemisinin
|
|
gptkbp:interacts_with
|
may interact with other medications
|
|
gptkbp:invention
|
patented compound
patent expired in 2011
|
|
gptkbp:market_position
|
widely available
|
|
gptkbp:mass
|
282.34 g/mol
|
|
gptkbp:mechanism_of_action
|
inhibits parasite growth
|
|
gptkbp:metabolism
|
hepatic metabolism
|
|
gptkbp:origin
|
gptkb:traditional_medicine
|
|
gptkbp:pharmacokinetics
|
rapidly absorbed
|
|
gptkbp:production_source
|
plant extraction
|
|
gptkbp:replaces
|
gptkb:1972
|
|
gptkbp:research_areas
|
antimalarial drug development
|
|
gptkbp:research_focus
|
drug resistance
|
|
gptkbp:safety_features
|
generally well tolerated
|
|
gptkbp:side_effect
|
dizziness
nausea
allergic reactions
vomiting
|
|
gptkbp:synergistic_effect
|
enhanced with other antimalarials
|
|
gptkbp:trade_names
|
gptkb:Artemisinin
|
|
gptkbp:treatment
|
gptkb:artemisinin-based_combination_therapies_(ACTs)
|
|
gptkbp:used_for
|
treating malaria
|
|
gptkbp:bfsParent
|
gptkb:Tu_Youyou
|
|
gptkbp:bfsLayer
|
6
|