Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:chemical_compound
|
| gptkbp:bfsLayer |
5
|
| gptkbp:bfsParent |
gptkb:Plasmodium
gptkb:Tu_Youyou |
| gptkbp:activities |
inhibits parasite growth
|
| gptkbp:antagonist |
high efficacy
|
| gptkbp:awards |
gptkb:Nobel_Prize_in_Physiology_or_Medicine_2015
|
| gptkbp:challenges |
supply chain issues
|
| gptkbp:class |
sesquiterpene lactone
|
| gptkbp:clinical_trial |
ongoing studies
variable absorption first-line treatment for uncomplicated malaria |
| gptkbp:community_impact |
significant in malaria control
|
| gptkbp:composed_of |
semi-synthetic methods
|
| gptkbp:cultural_significance |
part of traditional medicine practices
|
| gptkbp:defense |
recommended for malaria treatment
|
| gptkbp:developed_by |
gptkb:sweet_wormwood
|
| gptkbp:discovered_by |
gptkb:Tu_Youyou
|
| gptkbp:dissolved |
soluble in organic solvents
|
| gptkbp:excretion |
renal excretion
|
| gptkbp:financial_performance |
sensitive to light and heat
|
| gptkbp:formulation |
oral and injectable forms
|
| gptkbp:future_plans |
new formulations and delivery methods
|
| gptkbp:healthcare |
important for public health initiatives
|
| gptkbp:historical_significance |
revolutionized malaria treatment
|
| https://www.w3.org/2000/01/rdf-schema#label |
artemisinin
|
| gptkbp:ingredients |
C15 H22 O5
|
| gptkbp:interacts_with |
may interact with other medications
|
| gptkbp:invention |
patented compound
patent expired in 2011 |
| gptkbp:is_used_for |
treating malaria
|
| gptkbp:market |
widely available
|
| gptkbp:mass |
282.34 g/mol
|
| gptkbp:metabolism |
hepatic metabolism
|
| gptkbp:name |
gptkb:Artemisinin
|
| gptkbp:origin |
gptkb:product
|
| gptkbp:pharmacokinetics |
rapidly absorbed
|
| gptkbp:production_company |
plant extraction
|
| gptkbp:receives_funding_from |
supported by various organizations
|
| gptkbp:replaced_by |
gptkb:1972
|
| gptkbp:research_areas |
antimalarial drug development
|
| gptkbp:research_focus |
drug resistance
|
| gptkbp:safety_features |
generally well tolerated
|
| gptkbp:side_effect |
dizziness
nausea allergic reactions vomiting effective against Plasmodium species |
| gptkbp:synergizes_with |
enhanced with other antimalarials
|
| gptkbp:treatment |
artemisinin-based combination therapies (AC Ts)
|