sulfadoxine-pyrimethamine

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf combination drug
gptkbp:ATCCode P01BD51
gptkbp:combines gptkb:artesunate
gptkb:amodiaquine
gptkbp:contains gptkb:sulfadoxine
pyrimethamine
gptkbp:contraindication severe kidney disease
severe liver disease
sulfa allergy
gptkbp:discoveredBy 1960s
https://www.w3.org/2000/01/rdf-schema#label sulfadoxine-pyrimethamine
gptkbp:legalStatus prescription only
gptkbp:marketedAs gptkb:Fansidar
gptkbp:mechanismOfAction inhibits folic acid synthesis in Plasmodium
gptkbp:pregnancyCategory C (US)
gptkbp:resistanceReported yes
gptkbp:routeOfAdministration oral
gptkbp:sideEffect nausea
vomiting
rash
allergic reactions
gptkbp:usedFor malaria
intermittent preventive treatment in pregnancy
intermittent preventive treatment in infants
treatment of uncomplicated Plasmodium falciparum malaria
gptkbp:WHOModelListOfEssentialMedicines yes
gptkbp:bfsParent gptkb:Plasmodium_falciparum
gptkbp:bfsLayer 5