Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
estrogen synthase
|
| gptkbp:associatedWith |
gptkb:cancer
gynecomastia endometriosis |
| gptkbp:catalyzes |
conversion of androgens to estrogens
|
| gptkbp:cofactor |
oxygen
NADPH |
| gptkbp:EC_number |
1.14.14.14
|
| gptkbp:encodedBy |
CYP19A1 gene
|
| gptkbp:foundIn |
gptkb:skin
gptkb:placenta brain adipose tissue blood vessels gonads |
| gptkbp:gene |
gptkb:CYP19A1
|
| https://www.w3.org/2000/01/rdf-schema#label |
aromatase
|
| gptkbp:importantFor |
estrogen biosynthesis
|
| gptkbp:inhibitedBy |
aromatase inhibitors
|
| gptkbp:involves |
reproductive function
sexual differentiation |
| gptkbp:locatedOnChromosome |
gptkb:15q21.2_(human)
|
| gptkbp:molecularWeight |
about 55 kDa
|
| gptkbp:presentIn |
vertebrates
some invertebrates |
| gptkbp:structure |
cytochrome P450 enzyme
|
| gptkbp:systematicName |
estrogen synthetase
|
| gptkbp:target |
gptkb:letrozole
anastrozole exemestane |
| gptkbp:bfsParent |
gptkb:CYP19A1
|
| gptkbp:bfsLayer |
6
|