argininosuccinate synthetase 1

URI: https://gptkb.org/entity/argininosuccinate_synthetase_1
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName gptkb:ASS
gptkb:argininosuccinate_synthase
gptkbp:associatedWith gptkb:citrullinemia_type_I
gptkbp:biologicalProcess gptkb:urea_cycle
arginine biosynthetic process
argininosuccinate synthase activity
gptkbp:cofactor gptkb:ATP
gptkbp:EC_number 6.3.4.5
gptkbp:encodedBy ASS1 gene
gptkbp:expressedIn gptkb:kidney
liver
other tissues
gptkbp:function catalyzes the synthesis of argininosuccinate from citrulline and aspartate
gptkbp:gene gptkb:ASS1
gptkbp:HGNC_ID gptkb:HGNC:746
https://www.w3.org/2000/01/rdf-schema#label argininosuccinate synthetase 1
gptkbp:locatedOnChromosome 9q34.1
gptkbp:location cytosol
gptkbp:mutationAssociatedWith can cause citrullinemia type I
gptkbp:OMIM 603470
gptkbp:organism gptkb:Homo_sapiens
gptkbp:pathway gptkb:urea_cycle
gptkbp:PDB 1A8Z
gptkbp:product gptkb:AMP
argininosuccinate
pyrophosphate
gptkbp:RefSeq NM_000050
gptkbp:substrate gptkb:aspartate
citrulline
gptkbp:UniProtID P00966
gptkbp:bfsParent gptkb:argininosuccinate_synthetase
gptkbp:bfsLayer 6