Statements (49)
Predicate | Object |
---|---|
gptkbp:instanceOf |
autoimmune disease
syndrome |
gptkbp:affects |
all ages
immune system both men and women blood clotting |
gptkbp:alsoKnownAs |
gptkb:APS
Hughes syndrome |
gptkbp:associatedWith |
gptkb:systemic_lupus_erythematosus
|
gptkbp:canBePrimary |
yes
|
gptkbp:canBeSecondary |
yes
|
gptkbp:cause |
miscarriage
stroke pulmonary embolism deep vein thrombosis catastrophic antiphospholipid syndrome |
gptkbp:characterizedBy |
pregnancy complications
presence of antiphospholipid antibodies recurrent thrombosis |
gptkbp:commonIn |
gptkb:women
|
gptkbp:complication |
skin ulcers
seizures pulmonary hypertension thrombocytopenia organ damage heart valve disease chronic headaches |
gptkbp:diagnosedBy |
blood test for antiphospholipid antibodies
clinical criteria of thrombosis or pregnancy morbidity |
gptkbp:firstDescribed |
1983
Graham R.V. Hughes |
gptkbp:hasAntibody |
anti-beta2 glycoprotein I antibody
anticardiolipin antibody lupus anticoagulant |
https://www.w3.org/2000/01/rdf-schema#label |
antiphospholipid syndrome
|
gptkbp:ICD-10_code |
D68.6
|
gptkbp:prevalence |
rare
|
gptkbp:riskFactor |
venous thrombosis
arterial thrombosis recurrent pregnancy loss |
gptkbp:symptom |
stroke
livedo reticularis blood clots repeated miscarriages |
gptkbp:treatment |
gptkb:heparin
gptkb:aspirin anticoagulants |
gptkbp:bfsParent |
gptkb:Cerebral_Venous_Thrombosis
|
gptkbp:bfsLayer |
6
|