antiphospholipid syndrome

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf autoimmune disease
syndrome
gptkbp:affects all ages
immune system
both men and women
blood clotting
gptkbp:alsoKnownAs gptkb:APS
Hughes syndrome
gptkbp:associatedWith gptkb:systemic_lupus_erythematosus
gptkbp:canBePrimary yes
gptkbp:canBeSecondary yes
gptkbp:cause miscarriage
stroke
pulmonary embolism
deep vein thrombosis
catastrophic antiphospholipid syndrome
gptkbp:characterizedBy pregnancy complications
presence of antiphospholipid antibodies
recurrent thrombosis
gptkbp:commonIn gptkb:women
gptkbp:complication skin ulcers
seizures
pulmonary hypertension
thrombocytopenia
organ damage
heart valve disease
chronic headaches
gptkbp:diagnosedBy blood test for antiphospholipid antibodies
clinical criteria of thrombosis or pregnancy morbidity
gptkbp:firstDescribed 1983
Graham R.V. Hughes
gptkbp:hasAntibody anti-beta2 glycoprotein I antibody
anticardiolipin antibody
lupus anticoagulant
https://www.w3.org/2000/01/rdf-schema#label antiphospholipid syndrome
gptkbp:ICD-10_code D68.6
gptkbp:prevalence rare
gptkbp:riskFactor venous thrombosis
arterial thrombosis
recurrent pregnancy loss
gptkbp:symptom stroke
livedo reticularis
blood clots
repeated miscarriages
gptkbp:treatment gptkb:heparin
gptkb:aspirin
anticoagulants
gptkbp:bfsParent gptkb:Cerebral_Venous_Thrombosis
gptkbp:bfsLayer 6