Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:syndrome
gptkb:autoimmune_disease |
| gptkbp:affects |
all ages
immune system both men and women blood clotting |
| gptkbp:alsoKnownAs |
gptkb:APS
Hughes syndrome |
| gptkbp:associatedWith |
gptkb:systemic_lupus_erythematosus
|
| gptkbp:canBePrimary |
yes
|
| gptkbp:canBeSecondary |
yes
|
| gptkbp:cause |
miscarriage
stroke pulmonary embolism deep vein thrombosis catastrophic antiphospholipid syndrome |
| gptkbp:characterizedBy |
pregnancy complications
presence of antiphospholipid antibodies recurrent thrombosis |
| gptkbp:commonIn |
gptkb:women
|
| gptkbp:complication |
skin ulcers
seizures pulmonary hypertension thrombocytopenia organ damage heart valve disease chronic headaches |
| gptkbp:diagnosedBy |
blood test for antiphospholipid antibodies
clinical criteria of thrombosis or pregnancy morbidity |
| gptkbp:firstDescribed |
1983
Graham R.V. Hughes |
| gptkbp:hasAntibody |
anti-beta2 glycoprotein I antibody
anticardiolipin antibody lupus anticoagulant |
| gptkbp:ICD-10_code |
D68.6
|
| gptkbp:prevalence |
rare
|
| gptkbp:riskFactor |
venous thrombosis
arterial thrombosis recurrent pregnancy loss |
| gptkbp:symptom |
stroke
livedo reticularis blood clots repeated miscarriages |
| gptkbp:treatment |
gptkb:heparin
gptkb:aspirin anticoagulants |
| gptkbp:bfsParent |
gptkb:Systemic_lupus_erythematosus
gptkb:Cerebral_Venous_Thrombosis gptkb:anti-phospholipid |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
antiphospholipid syndrome
|