antimicrobial resistance gene KPC
GPTKB entity
Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
blaKPC
|
| gptkbp:associatedWith |
hospital-acquired infections
|
| gptkbp:detects |
PCR
whole genome sequencing |
| gptkbp:discoveredBy |
gptkb:United_States
|
| gptkbp:firstReported |
1996
|
| gptkbp:foundIn |
gptkb:Bacteria
gptkb:Klebsiella_pneumoniae gptkb:Enterobacter_species |
| gptkbp:fullName |
gptkb:Klebsiella_pneumoniae_carbapenemase
|
| https://www.w3.org/2000/01/rdf-schema#label |
antimicrobial resistance gene KPC
|
| gptkbp:mechanismOfAction |
hydrolyzes carbapenems
|
| gptkbp:proteinFamily |
class A beta-lactamase
|
| gptkbp:publicHealthConcern |
yes
|
| gptkbp:resistantTo |
gptkb:beta-lactam_antibiotics
carbapenem antibiotics |
| gptkbp:significance |
causes multidrug resistance
|
| gptkbp:spreadTo |
horizontal gene transfer
|
| gptkbp:transmission |
plasmid-mediated
|
| gptkbp:bfsParent |
gptkb:FilmArray_Pneumonia_Panel
|
| gptkbp:bfsLayer |
7
|