anti-CRISPR proteins

GPTKB entity

Statements (27)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:canBe controlling CRISPR-based gene drives
improving safety of gene editing
temporal control of genome editing
gptkbp:discoveredIn Pseudomonas aeruginosa phages
gptkbp:example AcrE1
AcrF1
AcrIIA4
AcrVA1
gptkbp:firstDescribed 2013
gptkbp:foundIn bacteriophages
mobile genetic elements
gptkbp:function inhibit CRISPR-Cas systems
https://www.w3.org/2000/01/rdf-schema#label anti-CRISPR proteins
gptkbp:mechanismOfAction protein-protein interaction
DNA mimicry
blocking DNA binding
inhibiting nuclease activity
gptkbp:relatedTo phage-bacteria arms race
gptkbp:target gptkb:CRISPR-Cas3
gptkb:CRISPR-Cas9
CRISPR-Cas12a
CRISPR-Cas13a
gptkbp:usedIn gptkb:biotechnology
gene editing regulation
gptkbp:bfsParent gptkb:Cas9
gptkbp:bfsLayer 7