Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
ANGPTL3
ANGPLT3 angiopoietin-related protein 3 |
| gptkbp:associatedWith |
atherosclerosis
coronary artery disease familial combined hypolipidemia |
| gptkbp:discoveredIn |
2000
|
| gptkbp:encodedBy |
ANGPTL3 gene
|
| gptkbp:expressedIn |
liver
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
regulation of lipid metabolism
inhibition of lipoprotein lipase regulation of plasma triglyceride levels |
| gptkbp:HGNC_ID |
16010
|
| https://www.w3.org/2000/01/rdf-schema#label |
angiopoietin-like protein 3
|
| gptkbp:inhibitedBy |
gptkb:lipoprotein_lipase
endothelial lipase |
| gptkbp:locatedOnChromosome |
chromosome 1p31.3
|
| gptkbp:location |
blood plasma
secreted protein |
| gptkbp:OMIM |
604774
|
| gptkbp:regulates |
lipid metabolism
cholesterol levels triglyceride levels |
| gptkbp:structure |
contains coiled-coil domain
contains fibrinogen-like domain |
| gptkbp:target |
gptkb:evinacumab
therapeutic antibodies |
| gptkbp:UniProtID |
Q9Y5C1
|
| gptkbp:bfsParent |
gptkb:Evkeeza
|
| gptkbp:bfsLayer |
8
|