amphotericin B colloidal dispersion

URI: https://gptkb.org/entity/amphotericin_B_colloidal_dispersion
GPTKB entity
Statements (29)
Predicate Object
gptkbp:instanceOf gptkb:colloidal_drug_formulation
gptkb:antifungal_medication
gptkbp:activeIngredient gptkb:amphotericin_B
gptkbp:approvedBy gptkb:FDA
gptkbp:ATCCode gptkb:J02AA01
gptkbp:brand gptkb:Amphotec
Amphocil
gptkbp:developedTo reduce renal toxicity of amphotericin B
gptkbp:form colloidal dispersion with sodium cholesteryl sulfate
gptkbp:indication gptkb:cryptococcosis
gptkb:histoplasmosis
gptkb:zygomycosis
candidiasis
aspergillosis
blastomycosis
coccidioidomycosis
fungal infections in immunocompromised patients
gptkbp:mechanismOfAction binds to ergosterol in fungal cell membranes
gptkbp:reducedToxicityComparedTo gptkb:conventional_amphotericin_B
gptkbp:regulates prescription only
gptkbp:routeOfAdministration intravenous
gptkbp:sideEffect nephrotoxicity
infusion-related reactions
gptkbp:usedFor treatment of cryptococcal meningitis
treatment of systemic fungal infections
gptkbp:bfsParent gptkb:Amphotericin_B
gptkb:conventional_amphotericin_B
gptkbp:bfsLayer 8
https://www.w3.org/2000/01/rdf-schema#label amphotericin B colloidal dispersion