amphotericin B colloidal dispersion
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
antifungal medication
colloidal drug formulation |
| gptkbp:activeIngredient |
gptkb:amphotericin_B
|
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:ATCCode |
gptkb:J02AA01
|
| gptkbp:brand |
gptkb:Amphotec
Amphocil |
| gptkbp:developedTo |
reduce renal toxicity of amphotericin B
|
| gptkbp:form |
colloidal dispersion with sodium cholesteryl sulfate
|
| https://www.w3.org/2000/01/rdf-schema#label |
amphotericin B colloidal dispersion
|
| gptkbp:indication |
gptkb:cryptococcosis
gptkb:histoplasmosis gptkb:zygomycosis candidiasis aspergillosis blastomycosis coccidioidomycosis fungal infections in immunocompromised patients |
| gptkbp:mechanismOfAction |
binds to ergosterol in fungal cell membranes
|
| gptkbp:reducedToxicityComparedTo |
gptkb:conventional_amphotericin_B
|
| gptkbp:regulates |
prescription only
|
| gptkbp:routeOfAdministration |
intravenous
|
| gptkbp:sideEffect |
nephrotoxicity
infusion-related reactions |
| gptkbp:usedFor |
treatment of cryptococcal meningitis
treatment of systemic fungal infections |
| gptkbp:bfsParent |
gptkb:Amphotericin_B
|
| gptkbp:bfsLayer |
7
|