|
gptkbp:instanceOf
|
gptkb:antibiotic
|
|
gptkbp:approvedBy
|
1949
|
|
gptkbp:ATCCode
|
A07AA01
|
|
gptkbp:CASNumber
|
1404-04-2
|
|
gptkbp:chemicalFormula
|
C23H46N6O13
|
|
gptkbp:contraindication
|
gptkb:myasthenia_gravis
pregnancy
intestinal obstruction
|
|
gptkbp:discoveredBy
|
gptkb:Selman_Waksman
|
|
gptkbp:discoveredIn
|
1949
|
|
gptkbp:eliminationHalfLife
|
2-3 hours
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:foundIn
|
gptkb:Neosporin
triple antibiotic ointment
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
neomycin
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits protein synthesis
binds 30S ribosomal subunit
|
|
gptkbp:meltingPoint
|
>260°C
|
|
gptkbp:metabolism
|
not significantly metabolized
|
|
gptkbp:molecularWeight
|
614.64 g/mol
|
|
gptkbp:pregnancyCategory
|
D (US)
|
|
gptkbp:producedBy
|
Streptomyces fradiae
|
|
gptkbp:PubChem_CID
|
8378
DB00994
|
|
gptkbp:riskFactor
|
hearing loss
kidney damage
|
|
gptkbp:routeOfAdministration
|
oral
topical
|
|
gptkbp:sideEffect
|
nephrotoxicity
allergic reactions
ototoxicity
|
|
gptkbp:solubility
|
water soluble
|
|
gptkbp:UNII
|
7JIE9NJ97Q
|
|
gptkbp:usedFor
|
bacterial infections
bowel preparation
topical infections
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
yes
|
|
gptkbp:bfsParent
|
gptkb:Aminoglycosides
|
|
gptkbp:bfsLayer
|
5
|