|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:activatedBy
|
gptkb:ATP
|
|
gptkbp:alternativeName
|
myokinase
|
|
gptkbp:associatedWith
|
gptkb:anemia
|
|
gptkbp:catalyzes
|
ATP + AMP ⇌ 2 ADP
|
|
gptkbp:cofactor
|
magnesium
|
|
gptkbp:conservedIn
|
prokaryotes
eukaryotes
|
|
gptkbp:discoveredBy
|
1950s
|
|
gptkbp:EC_number
|
2.7.4.3
|
|
gptkbp:enzymeClassification
|
transferase
|
|
gptkbp:foundIn
|
gptkb:Bacteria
mitochondria
cytosol
eukaryotes
|
|
gptkbp:function
|
nucleotide metabolism
energy homeostasis
|
|
gptkbp:gene
|
gptkb:AK
AK1
AK2
AK3
AK4
AK5
AK6
AK7
|
|
gptkbp:GO_term
|
GO:0004017
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
adenylate kinase
|
|
gptkbp:inhibitedBy
|
gptkb:AMP
Ap5A
|
|
gptkbp:location
|
gptkb:cytoplasm
gptkb:mitochondrial_intermembrane_space
|
|
gptkbp:molecularWeight
|
~21 kDa
|
|
gptkbp:PDB
|
1AKE
|
|
gptkbp:presentIn
|
all living cells
|
|
gptkbp:product
|
gptkb:ADP
|
|
gptkbp:proteinFamily
|
adenylate kinase family
|
|
gptkbp:regulates
|
adenine nucleotide levels
|
|
gptkbp:structure
|
dimer
monomer
|
|
gptkbp:substrate
|
gptkb:ATP
gptkb:AMP
nucleoside monophosphates
|
|
gptkbp:UniProtID
|
P00568 (human AK1)
|
|
gptkbp:used_in
|
diagnostic tests
biochemical assays
|
|
gptkbp:bfsParent
|
gptkb:CHEBI:36208
|
|
gptkbp:bfsLayer
|
6
|