|
gptkbp:instanceOf
|
gptkb:chemical_compound
gptkb:anticoagulant
analgesic
antipyretic
nonsteroidal anti-inflammatory drug
|
|
gptkbp:affiliatedWith
|
gptkb:salicylates
acetates
|
|
gptkbp:ATCCode
|
gptkb:N02BA01
|
|
gptkbp:brand
|
gptkb:Aspirin
|
|
gptkbp:CASNumber
|
50-78-2
|
|
gptkbp:chemicalFormula
|
C9H8O4
|
|
gptkbp:contraindication
|
asthma
peptic ulcer
children with viral infections
|
|
gptkbp:discoveredBy
|
gptkb:Felix_Hoffmann
|
|
gptkbp:discoveredIn
|
1897
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:foundIn
|
pharmaceutical drugs
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
acetylsalicylic acid
|
|
gptkbp:IUPACName
|
2-acetoxybenzoic acid
|
|
gptkbp:KEGGID
|
D00109
|
|
gptkbp:legalStatus
|
OTC (over-the-counter)
|
|
gptkbp:mechanismOfAction
|
reduces prostaglandin synthesis
inhibits cyclooxygenase (COX)
|
|
gptkbp:meltingPoint
|
135°C
|
|
gptkbp:MeSH_ID
|
D001241
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
180.16 g/mol
|
|
gptkbp:pregnancyCategory
|
C (US)
D (third trimester, US)
|
|
gptkbp:PubChem_CID
|
2244
CHEMBL25
DB00945
|
|
gptkbp:relatedTo
|
gptkb:acetyl_chloride
gptkb:salicylic_acid
acetic anhydride
|
|
gptkbp:riskFactor
|
gptkb:Reye's_syndrome_in_children
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
rectal
|
|
gptkbp:sideEffect
|
gastrointestinal bleeding
ulcers
allergic reactions
|
|
gptkbp:solubility
|
3 g/L (20°C)
|
|
gptkbp:UNII
|
R16CO5Y76E
|
|
gptkbp:usedFor
|
pain relief
fever reduction
inflammation reduction
prevention of blood clots
|
|
gptkbp:usedIn
|
stroke prevention
cardiovascular disease prevention
myocardial infarction prevention
|
|
gptkbp:bfsParent
|
gptkb:Bayer_Aspirin
gptkb:Bayer_Aspirin_(analgesic)
|
|
gptkbp:bfsLayer
|
6
|