|
gptkbp:instanceOf
|
gptkb:chemical_compound
class of drugs
|
|
gptkbp:antidote
|
hemodialysis
sodium bicarbonate
activated charcoal
|
|
gptkbp:cause
|
gptkb:Reye's_syndrome_in_children
|
|
gptkbp:chemicalFormula
|
C7H6O3 (for salicylic acid)
|
|
gptkbp:contains
|
gptkb:salicylic_acid
|
|
gptkbp:contraindication
|
children with viral infections
|
|
gptkbp:derivedFrom
|
gptkb:willow_bark
meadowsweet
|
|
gptkbp:discoveredBy
|
gptkb:Raffaele_Piria
|
|
gptkbp:excretion
|
kidneys
|
|
gptkbp:firstSynthesized
|
19th century
|
|
gptkbp:foundIn
|
gptkb:diflunisal
gptkb:salsalate
gptkb:aspirin
methyl salicylate
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
salicylates
|
|
gptkbp:mechanismOfAction
|
inhibits cyclooxygenase (COX) enzymes
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:overdoseLeadsTo
|
salicylate poisoning
|
|
gptkbp:sideEffect
|
tinnitus
gastrointestinal irritation
bleeding risk
|
|
gptkbp:usedFor
|
pain relief
anti-inflammatory
fever reduction
|
|
gptkbp:usedIn
|
oral medications
liniments
topical creams
|
|
gptkbp:bfsParent
|
gptkb:Bayer_Aspirin_(analgesic)
|
|
gptkbp:bfsLayer
|
6
|