XPF-ERCC1 complex

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:associatedWith gptkb:Fanconi_anemia
gptkb:xeroderma_pigmentosum
cancer susceptibility
gptkbp:biologicalProcess structure-specific endonuclease activity
gptkbp:component ERCC1 protein
XPF protein
gptkbp:function DNA repair
nucleotide excision repair
interstrand crosslink repair
gptkbp:gene ERCC1 gene
ERCC4 gene
https://www.w3.org/2000/01/rdf-schema#label XPF-ERCC1 complex
gptkbp:interactsWith gptkb:gene
other DNA repair proteins
gptkbp:mutationAssociatedWith genomic instability
increased sensitivity to DNA-damaging agents
gptkbp:organism gptkb:Homo_sapiens
gptkbp:PDB 2A1I
6S5M
gptkbp:subcellularLocation gptkb:nucleus
gptkbp:bfsParent gptkb:SLX4_protein
gptkbp:bfsLayer 7