Statements (43)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
epileptic syndrome
|
| gptkbp:alsoKnownAs |
infantile spasms
West syndrome |
| gptkbp:associatedWith |
gptkb:autism_spectrum_disorder
intellectual disability |
| gptkbp:canBeIdiopathic |
yes
|
| gptkbp:cause |
gptkb:tuberous_sclerosis
gptkb:Down_syndrome perinatal asphyxia |
| gptkbp:characterizedBy |
developmental regression
epileptic spasms hypsarrhythmia |
| gptkbp:complication |
gptkb:Lennox-Gastaut_syndrome
|
| gptkbp:diagnosedBy |
gptkb:EEG
clinical observation |
| gptkbp:EEGPattern |
hypsarrhythmia
|
| gptkbp:firstDescribed |
1841
William James West |
| gptkbp:frequency |
1 in 2,500 to 1 in 6,000 live births
|
| gptkbp:gender |
male predominance
|
| https://www.w3.org/2000/01/rdf-schema#label |
West Syndrome Epilepsy
|
| gptkbp:ICD-10_code |
G40.4
|
| gptkbp:MeSH_ID |
D013580
|
| gptkbp:mortalityRate |
increased compared to general population
|
| gptkbp:OMIM |
308350
|
| gptkbp:onset |
infancy
|
| gptkbp:parentOrganization |
International League Against Epilepsy (ILAE) classification
|
| gptkbp:peakOnsetAge |
3 to 12 months
|
| gptkbp:prevalence |
rare
|
| gptkbp:prognosis |
variable
often poor |
| gptkbp:relatedTo |
Epilepsy
|
| gptkbp:riskFactor |
genetic disorders
metabolic disorders structural brain abnormalities |
| gptkbp:symptom |
clusters of spasms
sudden flexion or extension of limbs |
| gptkbp:treatment |
gptkb:vigabatrin
gptkb:adrenocorticotropic_hormone corticosteroids antiepileptic drugs |
| gptkbp:bfsParent |
gptkb:D004239
|
| gptkbp:bfsLayer |
8
|