|
gptkbp:instanceOf
|
gptkb:epileptic_syndrome
|
|
gptkbp:alsoKnownAs
|
infantile spasms
West syndrome
|
|
gptkbp:associatedWith
|
gptkb:intellectual_disability
gptkb:autism_spectrum_disorder
|
|
gptkbp:canBeIdiopathic
|
yes
|
|
gptkbp:cause
|
gptkb:tuberous_sclerosis
gptkb:Down_syndrome
perinatal asphyxia
|
|
gptkbp:characterizedBy
|
developmental regression
epileptic spasms
hypsarrhythmia
|
|
gptkbp:complication
|
gptkb:Lennox-Gastaut_syndrome
|
|
gptkbp:diagnosedBy
|
gptkb:EEG
clinical observation
|
|
gptkbp:EEGPattern
|
hypsarrhythmia
|
|
gptkbp:firstDescribed
|
1841
William James West
|
|
gptkbp:frequency
|
1 in 2,500 to 1 in 6,000 live births
|
|
gptkbp:gender
|
male predominance
|
|
gptkbp:ICD-10_code
|
G40.4
|
|
gptkbp:MeSH_ID
|
D013580
|
|
gptkbp:mortalityRate
|
increased compared to general population
|
|
gptkbp:OMIM
|
308350
|
|
gptkbp:onset
|
infancy
|
|
gptkbp:parentOrganization
|
International League Against Epilepsy (ILAE) classification
|
|
gptkbp:peakOnsetAge
|
3 to 12 months
|
|
gptkbp:prevalence
|
rare
|
|
gptkbp:prognosis
|
variable
often poor
|
|
gptkbp:relatedTo
|
gptkb:Epilepsy
|
|
gptkbp:riskFactor
|
genetic disorders
metabolic disorders
structural brain abnormalities
|
|
gptkbp:symptom
|
clusters of spasms
sudden flexion or extension of limbs
|
|
gptkbp:treatment
|
gptkb:vigabatrin
gptkb:adrenocorticotropic_hormone
corticosteroids
antiepileptic drugs
|
|
gptkbp:bfsParent
|
gptkb:D004239
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
West Syndrome Epilepsy
|