|
gptkbp:instanceOf
|
gptkb:Epilepsy
gptkb:neurological_disorder
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|
gptkbp:causedBy
|
brain injury
infections
genetic mutations
unknown in many cases
|
|
gptkbp:comorbidity
|
gptkb:intellectual_disability
gptkb:autism_spectrum_disorder
|
|
gptkbp:frequency
|
1-2% of all childhood epilepsies
|
|
gptkbp:hasEEGPattern
|
slow spike-and-wave discharges
|
|
gptkbp:hasOrphanetID
|
ORPHA:2386
|
|
gptkbp:hasSeizureType
|
atonic seizures
atypical absence seizures
tonic seizures
|
|
gptkbp:ICD-10_code
|
G40.4
|
|
gptkbp:mortalityRate
|
higher than general epilepsy population
|
|
gptkbp:namedAfter
|
Henri Gastaut
William G. Lennox
|
|
gptkbp:OMIM
|
606369
|
|
gptkbp:onset
|
childhood
between 2 and 8 years
|
|
gptkbp:prevalence
|
rare
|
|
gptkbp:prognosis
|
often poor
|
|
gptkbp:symptom
|
cognitive impairment
behavioral problems
multiple seizure types
|
|
gptkbp:treatment
|
gptkb:ketogenic_diet
gptkb:vagus_nerve_stimulation
gptkb:corpus_callosotomy
antiepileptic drugs
|
|
gptkbp:bfsParent
|
gptkb:Epidiolex
gptkb:lamotrigine
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Lennox-Gastaut syndrome
|