Waldenström's macroglobulinemia
GPTKB entity
Statements (36)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
leukemia lymphoproliferative disorder |
| gptkbp:affects |
gptkb:B_lymphocytes
|
| gptkbp:alsoKnownAs |
lymphoplasmacytic lymphoma with IgM monoclonal gammopathy
|
| gptkbp:associatedWith |
MYD88 L265P mutation
|
| gptkbp:characterizedBy |
overproduction of IgM antibody
|
| gptkbp:complication |
heart failure
amyloidosis vision problems cryoglobulinemia |
| gptkbp:diagnosedBy |
bone marrow biopsy
serum protein electrophoresis |
| gptkbp:firstDescribed |
1944
|
| https://www.w3.org/2000/01/rdf-schema#label |
Waldenström's macroglobulinemia
|
| gptkbp:ICD-10_code |
C88.0
|
| gptkbp:medianAge |
60-70 years
|
| gptkbp:namedAfter |
gptkb:Jan_G._Waldenström
|
| gptkbp:origin |
lymphoplasmacytic cells
|
| gptkbp:parent |
leukemia
|
| gptkbp:prevalence |
rare
|
| gptkbp:prognosis |
variable
median survival 5-10 years |
| gptkbp:riskFactor |
male sex
family history of lymphoproliferative disorders |
| gptkbp:symptom |
gptkb:anemia
bleeding fatigue peripheral neuropathy hyperviscosity syndrome |
| gptkbp:treatment |
gptkb:rituximab
gptkb:ibrutinib chemotherapy plasmapheresis |
| gptkbp:bfsParent |
gptkb:Georges_Pompidou
|
| gptkbp:bfsLayer |
5
|