Waldenström's macroglobulinemia

URI: https://gptkb.org/entity/Waldenström's_macroglobulinemia
GPTKB entity
Statements (36)
Predicate Object
gptkbp:instanceOf gptkb:leukemia
gptkb:lymphoproliferative_disorder
gptkb:disease
gptkbp:affects gptkb:B_lymphocytes
gptkbp:alsoKnownAs lymphoplasmacytic lymphoma with IgM monoclonal gammopathy
gptkbp:associatedWith MYD88 L265P mutation
gptkbp:characterizedBy overproduction of IgM antibody
gptkbp:complication gptkb:amyloidosis
heart failure
vision problems
cryoglobulinemia
gptkbp:diagnosedBy bone marrow biopsy
serum protein electrophoresis
gptkbp:firstDescribed 1944
gptkbp:ICD-10_code C88.0
gptkbp:medianAge 60-70 years
gptkbp:namedAfter gptkb:Jan_G._Waldenström
gptkbp:origin lymphoplasmacytic cells
gptkbp:parent gptkb:leukemia
gptkbp:prevalence rare
gptkbp:prognosis variable
median survival 5-10 years
gptkbp:riskFactor male sex
family history of lymphoproliferative disorders
gptkbp:symptom gptkb:peripheral_neuropathy
gptkb:anemia
bleeding
fatigue
hyperviscosity syndrome
gptkbp:treatment gptkb:rituximab
gptkb:ibrutinib
chemotherapy
plasmapheresis
gptkbp:bfsParent gptkb:Georges_Pompidou
gptkbp:bfsLayer 5
https://www.w3.org/2000/01/rdf-schema#label Waldenström's macroglobulinemia