Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
Arp2/3 complex
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:domain |
proline-rich region
GTPase-binding domain VCA domain WH1 domain |
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:fullName |
Wiskott–Aldrich syndrome protein family
|
| gptkbp:function |
signal transduction
regulation of actin cytoskeleton |
| gptkbp:hasMember |
gptkb:WASP
gptkb:WASH gptkb:WAVE1 gptkb:WAVE2 gptkb:WAVE3 N-WASP JMY WHAMM |
| https://www.w3.org/2000/01/rdf-schema#label |
WASP family proteins
|
| gptkbp:interactsWith |
gptkb:Rac1
gptkb:Cdc42 profilin SH3 domain-containing proteins |
| gptkbp:involvedIn |
phagocytosis
cell motility endocytosis |
| gptkbp:mutationAssociatedWith |
immunodeficiency
Wiskott–Aldrich syndrome |
| gptkbp:proteinFamily |
WAS gene family
|
| gptkbp:regulates |
actin polymerization
|
| gptkbp:bfsParent |
gptkb:WAVE_complex
gptkb:WAC-1 |
| gptkbp:bfsLayer |
8
|