|
gptkbp:instanceOf
|
gptkb:drug
antidepressant
norepinephrine reuptake inhibitor
serotonin receptor agonist
|
|
gptkbp:approvedBy
|
2011 (US)
|
|
gptkbp:ATCCode
|
N06AB10
|
|
gptkbp:brand
|
gptkb:Viibryd
|
|
gptkbp:CASNumber
|
163521-12-8
|
|
gptkbp:chemicalClass
|
indolecarboxamide
|
|
gptkbp:contraindication
|
use with MAO inhibitors
|
|
gptkbp:developer
|
gptkb:Merck
gptkb:Forest_Laboratories
|
|
gptkbp:eliminationHalfLife
|
25 hours
|
|
gptkbp:hasMolecularFormula
|
C26H27N5O2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Vilazodone
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
selective serotonin reuptake inhibitor
5-HT1A receptor partial agonist
|
|
gptkbp:meltingPoint
|
215-217°C
|
|
gptkbp:metabolism
|
liver (CYP3A4, CYP2C19, CYP2D6)
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:proteinBinding
|
96-99%
|
|
gptkbp:PubChem_CID
|
5293726
6918347
DB06684
|
|
gptkbp:riskFactor
|
gptkb:serotonin_syndrome
suicidal thoughts (in young adults and children)
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
diarrhea
headache
insomnia
|
|
gptkbp:smiles
|
CCN(CC)CCNC(=O)C1=CC2=C(N1)C=CC=C2OC3=CC=CC=C3C(=O)N
|
|
gptkbp:synonym
|
gptkb:EMD_68843
gptkb:Viibryd
|
|
gptkbp:UNII
|
O3P71G0N7I
|
|
gptkbp:usedFor
|
gptkb:major_depressive_disorder
|
|
gptkbp:bfsParent
|
gptkb:Antidepressants
|
|
gptkbp:bfsLayer
|
6
|